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Heart disease is exacerbated by inflammation which can be caused by bacteria from 'icky'gums.
Study makes first connection between heart disorder and Alzheimer's disease
Study of more than 37,000 patients shows relationship between atrial fibrillation and development of Alzheimer's disease
Researchers at Intermountain Medical Center in Salt Lake City believe
that they have made a breakthrough connection between atrial
fibrillation, a fairly common heart rhythm disorder, and Alzheimer's
disease, the leading form of dementia among Americans.
In a study presented Friday, May 15, at "Heart Rhythm 2009," the annual
scientific sessions of the Heart Rhythm Society in Boston, researchers
unveiled findings from the study of more than 37,000 patients that
showed a strong relationship between atrial fibrillation and the
development of Alzheimer's disease.
The study, which drew upon information from the Intermountain Heart
Collaborative Study, a vast database from hundreds of thousands of
patients treated at Intermountain Healthcare hospitals, found:
• Patients with atrial fibrillation were 44 percent more likely to develop dementia than patients without the heart disorder.
• Younger patients with atrial fibrillation were at higher risk of developing all types of dementia, particularly Alzheimer's. Atrial
fibrillation patients under age 70 were 130 percent more likely to develop Alzheimer's.
• Patients who have both atrial fibrillation and dementia were 61 percent more likely to die during the study period than dementia
patients without the rhythm problem.
• Younger atrial fibrillation patients with dementia may be at higher risk of death than older AF patients with dementia.
Brush your teeth...floss to keep from worsening your other diseases!
Intermountain Medical Center cardiologist T. Jared Bunch, M.D., the study's lead researcher, presented the findings at the scientific session.
"Previous studies have shown that patients with atrial fibrillation are at higher risk for some types of dementia, including vascular dementia.
But to our knowledge, this is the first large-population study to clearly show that having atrial fibrillation puts patients at greater
risk for developing Alzheimer's disease," said Dr. Bunch.
Currently, the known risk factors for Alzheimer's are age, family
history and genetics, though injury may also be linked with the disease.
Heart health has long been suspected to play a role, but has not been linked. The Intermountain Medical Center study bolsters that connection.
"The study shows a connection between atrial fibrillation and all types of dementia," said Bunch. "The Alzheimer's findings — particularly the risk of death for younger patients — break new ground."
Atrial fibrillation is the most common heart rhythm problem, affecting about 2.2 million Americans. It occurs when the heart beats chaotically, leading blood to pool and possibly clot. If the clot leaves the heart, a stroke can result.
"Now that we've established this link, our focus will be to see if early treatment of atrial fibrillation can prevent dementia or the development of Alzheimer's disease," says cardiologist John Day, M.D., director of
heart rhythm services at Intermountain Medical Center and a co-author of the study.
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News News News News News News
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Research says older people need more sun
Spending more time in the sunshine could help older people to reduce
their risk of developing heart disease and diabetes.
Exposure to sunlight stimulates vitamin D in the skin and older people
are more likely to have a vitamin D deficiency due to the natural aging
process and changes in lifestyle.
Researchers at the University of Warwick have shown vitamin D deficiency
is significantly associated with metabolic syndrome, a combination of
medical and metabolic disorders that increase the risk of developing
cardiovascular disease and diabetes.
The research team, led by Dr Oscar Franco at Warwick Medical School,
investigated the association between vitamin D levels in the blood and
the prevalence of metabolic syndrome in 3,262 people aged 50-70 years
old in China.
His team found a high correlation between low vitamin D levels and the
prevalence of metabolic syndrome. They found 94% of people in the study
had a vitamin D (25-hydroxyvitamin D) deficiency or insufficiency. The
results showed 42.3% of these people also had metabolic syndrome.
The results of the study, published in Diabetes Care journal, are
consistent with the findings of other studies in Western populations and
Dr Franco suggests vitamin D deficiency could become a global health
problem.
He said: "Vitamin D deficiency is becoming a condition that is causing a
large burden of disease across the globe with particular deleterious
impact among the elderly. Our results are consistent with those found in
British and American populations. We found that low vitamin D levels
were associated with an increased risk of having metabolic syndrome, and
was also significantly associated with increased insulin resistance."
Dr Franco said there were many factors which could explain why older
people had less vitamin D in their blood, including changes in lifestyle
factors such as clothing and outdoor activity.
He added: "As we get older our skin is less efficient at forming vitamin
D and our diet may also become less varied, with a lower natural vitamin
D content. Most importantly, however, the dermal production of vitamin D
following a standard exposure to UVB light decreases with age because of
atrophic skin changes. When we are older we may need to spend more time
outdoors to stimulate the same levels of vitamin D we had when we were
younger."
Vitamin D deficiency exists when the concentration of 25-hydroxy-vitamin
D (25-OH-D) in the blood serum occurs at 12ng/ml (nanograms/millilitre)
or less. The normal concentration of 25-hydroxy-vitamin D in the blood
serum is 25-50ng/ml.
This study was carried out in collaboration with colleagues from the
Shanghai Institute of Biological Sciences in China. The team recruited
3,262 community residents aged 50-70 from Beijing and Shanghai in China
as part of the Nutrition and Health of Aging Population in China (NHAPC)
project.
Dr Franco added: "Vitamin D deficiency is now recognised as a worldwide
concern and metabolic syndrome has become a global epidemic. More
research is needed to find out why older people are more likely to have
lower levels of vitamin D and how this is linked to the development of
metabolic syndrome and related metabolic diseases."
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